Bufotalin Induces Oxidative Stress-Mediated Apoptosis by Blocking the ITGB4/FAK/ERK Pathway in Glioblastoma
Bufotalin (BT), a major active constituent of Chansu, has been found to possess multiple pharmacological activities. Although previous studies have shown that BT could inhibit the growth of glioblastoma (GBM), the safety of BT in vivo and the potential mechanism are still unclear. We conducted a sys...
Saved in:
Main Authors: | Junchao Tan (Author), Guoqiang Lin (Author), Rui Zhang (Author), Yuting Wen (Author), Chunying Luo (Author), Ran Wang (Author), Feiyun Wang (Author), Shoujiao Peng (Author), Jiange Zhang (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2024-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
miR-497 defect contributes to gastric cancer tumorigenesis and progression via regulating CDC42/ITGB1/FAK/PXN/AKT signaling
by: Lihui Zhang, et al.
Published: (2021) -
Psoralidin inhibits osteosarcoma growth and metastasis by downregulating ITGB1 expression via the FAK and PI3K/Akt signaling pathways
by: Shengwen Cheng, et al.
Published: (2023) -
Interaction between FAK/αB-crystalline is important for viability of the glioblastoma cells
by: Mariany Lopes da Costa Folly, et al.
Published: (2024) -
PGE2 Promotes the Migration of Mesenchymal Stem Cells through the Activation of FAK and ERK1/2 Pathway
by: Xiaomin Lu, et al.
Published: (2017) -
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
by: Zi-Ru Dai, et al.
Published: (2019)