A Novel Effect of Bifemelane, a Nootropic Drug, on Intracellular Ca2+ Levels in Rat Cerebral Astrocytes

• Main Authors: Yoshitoku Yoshida (Author), Akira Nakane (Author), Mitsuhiro Morita (Author), Yoshihisa Kudo (Author)
• Formato: Livro
• Publicado em: Elsevier, 2006-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract.: We investigated the effects of bifemelane, a nootropic drug, on the intracellular calcium concentration ([Ca2+]i) in rat cerebral astrocytes using a Ca2+ imaging device. At concentrations of 10 - 30 µM, bifemelane induced a slow onset and small increase in the [Ca2+]i, while at higher con...