Hydroa vacciniforme-like cutaneous T-cell lymphoma

A 14-year-old Chinese girl had a 6-year history of recurrent lesions on her head, face, and limbs. Epstein-Barr virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry...

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Bibliographic Details
Main Authors: Jian-Qiang Shi (Author), Qiu-Xia Chen (Author), Shun-Fan Li (Author), Wen Li (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2014-01-01T00:00:00Z.
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Summary:A 14-year-old Chinese girl had a 6-year history of recurrent lesions on her head, face, and limbs. Epstein-Barr virus (EBV)-IgM was positive. Histopathological findings revealed focal lymphocyte invasion in subcutaneous panniculus adiposus, mainly surrounding the blood vessels. Immunohistochemistry showed CD3+, CD4+, CD5+, CD8+, TIA-1+, GrB+, CD56-, and L26-. In situ hybridization staining for EBV-encoded small nonpolyadenylated RNA (EBER)-1 was positive. The patient showed significant improvement in clinical symptoms after being treated with acyclovir and IFN-α in this patient.
Item Description:0019-5154
1998-3611
10.4103/0019-5154.123516