Comparison of clot lysis activity and biochemical properties of originator tenecteplase (Metalyse®) with those of an alleged biosimilar

• Main Authors: Werner eKliche (Author), Ingo eKrech (Author), Martin C Michel (Author), Nishant V Sangole (Author), Sadhana eSathaye (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The bioengineered tissue plasminogen activator tenecteplase is an important treatment modality of acute myocardial infarction recommended by international guidelines. Following introduction of originator tenecteplase (brand names Metalyse® and TNKase®), a 'biosimilar' tenecteplase became a...