A comparative study of the preventive effect of chlorhexidine o. 12% and nano zinc oxide particles on the distraction of collagen scaffolding of the hybrid layer by two immunohistochemistry and microleakage tests
Introduction: Hybrid layer degradation is mainly attributed to matrix metalo proteinases (MMP) activity. In this study, we compare inhibitory effect of nano zinc oxide with chlorhexidine (0.12%) on distraction of collagen scaffolding of the hybrid layer by immunohistochemistry (IHC) and microleakage...
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Wolters Kluwer Medknow Publications,
2014-01-01T00:00:00Z.
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|---|---|---|---|
| 001 | doaj_e83f236a0771469a91a0dc9a2026d295 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Homayoon Alaghemand |e author |
| 700 | 1 | 0 | |a Behnaz Esmaeili |e author |
| 700 | 1 | 0 | |a Pouralibaba Firouz |e author |
| 700 | 1 | 0 | |a Mohammad Hossein Soltani |e author |
| 700 | 1 | 0 | |a Marzyeh Rouhaninasab |e author |
| 700 | 1 | 0 | |a Ali Dehghani nazhvani |e author |
| 700 | 1 | 0 | |a Ali Bijani |e author |
| 245 | 0 | 0 | |a A comparative study of the preventive effect of chlorhexidine o. 12% and nano zinc oxide particles on the distraction of collagen scaffolding of the hybrid layer by two immunohistochemistry and microleakage tests |
| 260 | |b Wolters Kluwer Medknow Publications, |c 2014-01-01T00:00:00Z. | ||
| 500 | |a 2348-1471 | ||
| 500 | |a 10.4103/2348-1471.143327 | ||
| 520 | |a Introduction: Hybrid layer degradation is mainly attributed to matrix metalo proteinases (MMP) activity. In this study, we compare inhibitory effect of nano zinc oxide with chlorhexidine (0.12%) on distraction of collagen scaffolding of the hybrid layer by immunohistochemistry (IHC) and microleakage tests. Materials and Methods: A total of 60 extracted molars and premolar teeth with no caries and visible anatomic defects were selected. Class 5 cavities with dimensions of 2 × 2 × 2 mm was performed for each tooth on the buccal surface 1 mm above cemento enamel junction. Results: In microleakage test, there was no significant difference in the result for groups pretreated with nano zinc oxide mixed with single bond (C), pretreated with chlorhexidine (0.12%) applied before bonding (B) and not pretreated with these agents (A) whether in 24 h or 1-week. in IHC test, there was a significant difference (P < 0.05) between all groups except in group B and group C. Conclusion: (1) The inhibitory effect of chlorhexidine and nano zinc oxide on MMPs activity is different. (2) Microleakage amount is different in composite resin restoration used in a cavity pretreated with nano zinc oxide contained bonding or chlorhexidine 24 h and 1-week later. | ||
| 546 | |a EN | ||
| 690 | |a Anatomic defects | ||
| 690 | |a immunohistochemistry | ||
| 690 | |a matrix metalo proteinases | ||
| 690 | |a Dentistry | ||
| 690 | |a RK1-715 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Dentistry and Medical Research, Vol 2, Iss 2, Pp 33-38 (2014) | |
| 787 | 0 | |n http://www.dmrjournal.org/article.asp?issn=2348-1471;year=2014;volume=2;issue=2;spage=33;epage=38;aulast=Alaghemand | |
| 787 | 0 | |n https://doaj.org/toc/2348-1471 | |
| 856 | 4 | 1 | |u https://doaj.org/article/e83f236a0771469a91a0dc9a2026d295 |z Connect to this object online. |