Analysis of HRAS mutations in Japanese patients with oral squamous cell carcinoma

• Autori principali: Masahiro Uchibori (Autore), Yuko Osawa (Autore), Yuuki Ishii (Autore), Takayuki Aoki (Autore), Yoshihide Ota (Autore), Minoru Kimura (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Objectives: The incidence of oral squamous cell carcinoma (OSCC) is associated with chewing tobacco and heavy consumption of alcohol. OSCC is also associated with Harvey rat sarcoma viral proto-oncogene homolog (HRAS) gene mutations, which are known to be high-risk factors for poor survival outcomes...