Analysis of HRAS mutations in Japanese patients with oral squamous cell carcinoma

• Principais autores: Masahiro Uchibori (Autor), Yuko Osawa (Autor), Yuuki Ishii (Autor), Takayuki Aoki (Autor), Yoshihide Ota (Autor), Minoru Kimura (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2021-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objectives: The incidence of oral squamous cell carcinoma (OSCC) is associated with chewing tobacco and heavy consumption of alcohol. OSCC is also associated with Harvey rat sarcoma viral proto-oncogene homolog (HRAS) gene mutations, which are known to be high-risk factors for poor survival outcomes...