Multiple myeloma and kidney disease

Abstract   Background: Multiple myeloma is a clonal plasma cell neoplasm which affects 1% of all malignancies. In this article we reviewed epidemiology, symptoms with particular attention to renal failure and its manifestation in multiple myeloma (MM). Material and methods: This paper was based on m...

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Main Authors: Natalia Zarankiewicz (Author), Katarzyna Kosz (Author), Martyna Zielińska (Author), Klaudia Remjasz (Author), Aleksandra Kuchnicka (Author), Julia Kuchnicka (Author), Klaudia Sapuła (Author), Jakub Aleksandrowicz (Author), Wojciech Siedlecki (Author)
Format: Book
Published: Kazimierz Wielki University, 2022-08-01T00:00:00Z.
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Summary:Abstract   Background: Multiple myeloma is a clonal plasma cell neoplasm which affects 1% of all malignancies. In this article we reviewed epidemiology, symptoms with particular attention to renal failure and its manifestation in multiple myeloma (MM). Material and methods: This paper was based on medical articles collected in PubMed from 2001 to 2022, medical websites and books. The research has been done by looking through key words such as: "multiple myeloma", "myeloma cast nephropathy", "bortezomib", "RANKL" Results: Multiple myeloma has indolent course and many patients present renal disorders at the moment of diagnosis. The use of novel therapies can reverse renal failure. Conclusions: Treatment of the patients with MM and kidney disease is challenging for health care professionals. Doctors have to adjust treatment to provide the best therapeutic effects.
Item Description:10.12775/JEHS.2022.12.08.089
2391-8306