RT001 in Progressive Supranuclear Palsy-Clinical and In-Vitro Observations

• Main Authors: Plamena R. Angelova (Author), Kristin M. Andruska (Author), Mark G. Midei (Author), Mario Barilani (Author), Paldeep Atwal (Author), Oliver Tucher (Author), Peter Milner (Author), Frederic Heerinckx (Author), Mikhail S. Shchepinov (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Progressive supranuclear palsy (PSP) is a progressive movement disorder associated with lipid peroxidation and intracerebral accumulation of tau. RT001 is a deuterium reinforced isotopologue of linoleic acid that prevents lipid peroxidation (LPO) through the kinetic isotope effect. The effects of RT...