The metabolomics of psoriatic disease

Di Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics&rdq...

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Main Authors: Yan D (Author), Afifi L (Author), Jeon C (Author), Trivedi M (Author), Chang HW (Author), Lee K (Author), Liao W (Author)
Format: Book
Published: Dove Medical Press, 2017-01-01T00:00:00Z.
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500 |a 2230-326X 
520 |a Di Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recently, metabolomics has been used to study the local and systemic metabolic changes in psoriasis and its cardiometabolic comorbidities. Such studies have revealed novel insights into disease pathogenesis and suggest new biochemical signatures that may be used as a marker of psoriatic disease. This review will discuss common strategies in metabolomics analysis, current findings in the metabolomics of psoriasis, and emerging trends in psoriatic metabolomics. Keywords: metabolome, psoriasis, psoriatic arthritis, skin, urine, metabolites 
546 |a EN 
690 |a Metabolome 
690 |a Psoriasis 
690 |a Psoriatic arthritis 
690 |a Skin 
690 |a Urine 
690 |a Metabolites 
690 |a Dermatology 
690 |a RL1-803 
655 7 |a article  |2 local 
786 0 |n Psoriasis: Targets and Therapy, Vol Volume 7, Pp 1-15 (2017) 
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