Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager

We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum an...

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Bibliographic Details
Main Authors: Taylor Wintler (Author), Monica Zherebtsov (Author), Susanne Carmack (Author), Rebecca Muntean (Author), Sarah J. Hill (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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Summary:We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child.
Item Description:2213-5766
10.1016/j.epsc.2021.102103