Association of <i> Helicobacter pylori</i> with lichen planus

<b>Background</b> : Lichen planus (LP) is a common idiopathic, inflammatory disorder that affects the skin, mucous membranes, nails and hair. Clinical observations and anecdotal reports have suggested a relationship between the exposure to a number of exogenous agents and the development...

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Main Authors: Moravvej Hamideh (Author), Hoseini Homa (Author), Barikbin Behrooz (Author), Malekzadeh Reza (Author), Razavi Gita (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2007-01-01T00:00:00Z.
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Summary:<b>Background</b> : Lichen planus (LP) is a common idiopathic, inflammatory disorder that affects the skin, mucous membranes, nails and hair. Clinical observations and anecdotal reports have suggested a relationship between the exposure to a number of exogenous agents and the development of LP. One of the most important suggested bacterial etiologies is <i> Helicobacter pylori </i> (HP), that is one of the most common bacterial infections in the world, which is also reported to be common in Iran. <b> Objective</b> : This study was performed to evaluate the relation between HP and LP. <b> Materials and Methods:</b> A case control study was conducted with 80 patients with LP to find out a previous history of HP and 80 patients with other skin diseases were examined with urea breath test (UBT) as controls. <b> Results:</b> Sixty-six patients with LP and 49 patients from the controls had positive UBT. There was a significant difference about UBT positive result between these two groups. <b> Conclusion:</b> According to study, these results support a definitive etiological role for HP in LP.
Item Description:0019-5154