Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements

The application of hydrodynamically closed capillary zone electrophoresis combined with convenient ultraviolet (UV) detection allows fast, simple, environmentally friendly and cost-effective analysis of ions or ionisable molecules. This technique has been used to determine two selected B vitamins (t...

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Bibliographic Details
Main Authors: Matuskova M. (Author), Cizmarova I. (Author), Chalova P. (Author), Mikus P. (Author), Piestansky J. (Author)
Format: Book
Published: Sciendo, 2021-07-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Matuskova M.  |e author 
700 1 0 |a Cizmarova I.  |e author 
700 1 0 |a Chalova P.  |e author 
700 1 0 |a Mikus P.  |e author 
700 1 0 |a Piestansky J.  |e author 
245 0 0 |a Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements 
260 |b Sciendo,   |c 2021-07-01T00:00:00Z. 
500 |a 2453-6725 
500 |a 10.2478/afpuc-2021-0002 
520 |a The application of hydrodynamically closed capillary zone electrophoresis combined with convenient ultraviolet (UV) detection allows fast, simple, environmentally friendly and cost-effective analysis of ions or ionisable molecules. This technique has been used to determine two selected B vitamins (thiamine, pyridoxine) in various drug formulations. The developed method was characterised by excellent validation parameters, such as linearity, precision, accuracy, limit of detection and limit of quantification. The total time of analysis was lower than 13.5 min. The results indicate that the method is suitable for implementation in routine quality control of selected B vitamins in pharmaceutical and food samples. 
546 |a EN 
690 |a capillary zone electrophoresis 
690 |a hydrodynamically closed system 
690 |a ultraviolet detection 
690 |a thiamine 
690 |a pyridoxine 
690 |a quality control 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n European Pharmaceutical Journal, Vol 68, Iss 1, Pp 59-62 (2021) 
787 0 |n https://doi.org/10.2478/afpuc-2021-0002 
787 0 |n https://doaj.org/toc/2453-6725 
856 4 1 |u https://doaj.org/article/e88d76fecf024fd1a385b08e96a35ff1  |z Connect to this object online.