The Possible Contribution of P-Glycoprotein in the Protective Effect of Paeonol against Methotrexate-Induced Testicular Injury in Rats
Paeonol, a phenolic ingredient in the genus <i>Paeonia</i>, possesses antioxidant and anti-inflammatory effects. Methotrexate (MTX) is a commonly used chemotherapeutic agent; however, its germ cell damage is a critical problem. P-glycoprotein (P-gp), an efflux transporter, is a member of...
Saved in:
Main Authors: | Mohamed A. Morsy (Author), Asmaa M. Abdel-Aziz (Author), Sara M. N. Abdel-Hafez (Author), Katharigatta N. Venugopala (Author), Anroop B. Nair (Author), Seham A. Abdel-Gaber (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Paeonol Protects against Methotrexate Hepatotoxicity by Repressing Oxidative Stress, Inflammation, and Apoptosis-The Role of Drug Efflux Transporters
by: Mohamed A. Morsy, et al.
Published: (2022) -
Paeonol Attenuates Hepatic Ischemia/Reperfusion Injury by Modulating the Nrf2/HO-1 and TLR4/MYD88/NF-κB Signaling Pathways
by: Mohamed A. Morsy, et al.
Published: (2022) -
Paeonol Protects Against Methotrexate-Induced Nephrotoxicity via Upregulation of P-gp Expression and Inhibition of TLR4/NF-κB Pathway
by: Mohamed A. Morsy, et al.
Published: (2022) -
Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway
by: Abdulla Y. Al-Taher, et al.
Published: (2020) -
Pregnenolone Inhibits Doxorubicin-Induced Cardiac Oxidative Stress, Inflammation, and Apoptosis-Role of Matrix Metalloproteinase 2 and NADPH Oxidase 1
by: Mohamed A. Morsy, et al.
Published: (2023)