European Mitochondrial DNA Haplogroups are Associated with Cerebrospinal Fluid Biomarkers of Inflammation in HIV Infection

• Main Authors: David C. Samuels (Author), Asha R. Kallianpur (Author), Ronald J. Ellis (Author), William S. Bush (Author), Scott Letendre (Author), Donald Franklin (Author), Igor Grant (Author), Todd Hulgan (Author)
• Format: Book
• Published: Case Western Reserve University, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Mitochondrial DNA (mtDNA) haplogroups are ancestry-related patterns of single-nucleotide polymorphisms that are associated with differential mitochondrial function in model systems, neurodegenerative diseases in HIV-negative populations, and chronic complications of HIV infection, includ...