Optimizing the DNA Donor Template for Homology-Directed Repair of Double-Strand Breaks
The CRISPR-Cas (clustered regularly interspaced short palindromic repeats-associated proteins) technology enables rapid and precise genome editing at any desired genomic position in almost all cells and organisms. In this study, we analyzed the impact of different repair templates on the frequency o...
Saved in:
Main Authors: | Fei Song (Author), Knut Stieger (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2017-06-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Regulation of DNA Double Strand Break Repair by Local Chromatin Architecture
Published: (2020) -
In Vivo Outcome of Homology-Directed Repair at the HBB Gene in HSC Using Alternative Donor Template Delivery Methods
by: Sowmya Pattabhi, et al.
Published: (2019) -
Simvastatin Sensitizes Radioresistant Prostate Cancer Cells by Compromising DNA Double-Strand Break Repair
by: Yu-An Chen, et al.
Published: (2018) -
Impact of DNA double-strand breaks on pancreaticobiliary maljunction carcinogenesis
by: Yasuhiro Kuraishi, et al.
Published: (2021) -
The in vivo and in vitro roles of Trypanosoma cruzi Rad51 in the repair of DNA double strand breaks and oxidative lesions.
by: Danielle Gomes Passos Silva, et al.
Published: (2018)