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Hair cell-specific Myo15 promoter-mediated gene therapy rescues hearing in DFNB9 mouse model

Adeno-associated viral (AAV) vectors are increasingly used as vehicles for gene delivery to treat hearing loss. However, lack of specificity of the transgene expression may lead to overexpression of the transgene in nontarget tissues. In this study, we evaluated the expression efficiency and specifi...

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Main Authors: Hui Wang (Author), MengZhao Xun (Author), Honghai Tang (Author), Jingjing Zhao (Author), Shaowei Hu (Author), Longlong Zhang (Author), Jun Lv (Author), Daqi Wang (Author), Yuxin Chen (Author), Jianping Liu (Author), Geng-lin Li (Author), Wuqing Wang (Author), Yilai Shu (Author), Huawei Li (Author)
Format: Book
Published: Elsevier, 2024-03-01T00:00:00Z.
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