Pulsatilla decoction alleviates DSS-induced UC by activating FXR-ASBT pathways to ameliorate disordered bile acids homeostasis

• Main Authors: Ying Xiao (Author), Ya-qian Jia (Author), Wen-juan Liu (Author), Chun Niu (Author), Zhan-hai Mai (Author), Jia-qi Dong (Author), Xiao-song Zhang (Author), Zi-wen Yuan (Author), Peng Ji (Author), Yan-ming Wei (Author), Yong-li Hua (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ethnopharmacological relevance: Pulsatilla decoction (PD) is a classical prescription for the treatment of ulcerative colitis. Previous studies have demonstrated that the therapeutic efficacy of PD is closely associated with the activation of Farnesoid X receptor (FXR). The activity of FXR is regula...