The Role of Organoids as a Novel Platform for Modeling of Inflammatory Bowel Disease

• Main Authors: Lauren O'Connell (Author), Des C. Winter (Author), Carol M. Aherne (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Inflammatory bowel disease (IBD) is a chronic relapsing-remitting immune-mediated disorder affecting the gut. It is common in Westernized regions and is increasing in incidence in developing countries. At a molecular level, intrinsic deficiencies in epithelial integrity, mucosal barrier function, an...