Bioinspired membrane-based nanomodulators for immunotherapy of autoimmune and infectious diseases

• Main Authors: Yesi Shi (Author), Hongyan Qian (Author), Peishi Rao (Author), Dan Mu (Author), Yuan Liu (Author), Gang Liu (Author), Zhongning Lin (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2022-03-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

סיכום

Autoimmune or infectious diseases often instigate the undesirable damages to tissues or organs to trigger immune-related diseases, which involve plenty of immune cells, pathogens and autoantibodies. Nanomedicine has a great potential in modulating immune system. Particularly, biomimetic nanomodulators can be designed for prevention, diagnosis and therapy to achieve a better targeted immunotherapy. With the development of materials science and bioengineering, a wide range of membrane-coated nanomodulators are available. Herein, we summarize recent advancements of bioinspired membrane-coated nanoplatform for systemic protection against immune-related diseases including autoimmune and infectious diseases. We also rethink the challenges or limitations in the progress of the therapeutic nanoplatform, and discuss the further application of the nanomodulators in the view of translational medicine for combating immune-related diseases.

תאור פריט

2211-3835
10.1016/j.apsb.2021.09.025