Medication-related osteonecrosis of the jaw: A review about etiology, risk factors, pathophysiology, and treatment

Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of antiresorptive and antiangiogenic medication. MRONJ is considered when a patient has exposed bone in the jaw for more than 8 weeks and has a history of antiresorptive and antiangiogenic medication with a negative hist...

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Bibliographic Details
Main Authors: Sheetal Singar (Author), Ajay Pratap Singh Parihar (Author), Prashanthi Reddy (Author), Abhishek Maurya (Author), Vishal Bamaniya (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
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100 1 0 |a Sheetal Singar  |e author 
700 1 0 |a Ajay Pratap Singh Parihar  |e author 
700 1 0 |a Prashanthi Reddy  |e author 
700 1 0 |a Abhishek Maurya  |e author 
700 1 0 |a Vishal Bamaniya  |e author 
245 0 0 |a Medication-related osteonecrosis of the jaw: A review about etiology, risk factors, pathophysiology, and treatment 
260 |b Wolters Kluwer Medknow Publications,   |c 2020-01-01T00:00:00Z. 
500 |a 0972-1363 
500 |a 10.4103/jiaomr.jiaomr_206_19 
520 |a Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of antiresorptive and antiangiogenic medication. MRONJ is considered when a patient has exposed bone in the jaw for more than 8 weeks and has a history of antiresorptive and antiangiogenic medication with a negative history of radiotherapy. Antiresorptive and antiangiogenic medication do not independently cause necrosis of bone. Various systemic and local risk factors like dentoalveolar trauma and extraction play an important role in the development of MRONJ. MRONJ can be prevented by proper dental evaluation and by performing the required treatment before commencing antiresorptive and antiangiogenic medication. 
546 |a EN 
690 |a antiangiogenic drugs 
690 |a antiresorptive drugs 
690 |a mronj 
690 |a osteonecrosis 
690 |a Dentistry 
690 |a RK1-715 
690 |a Medical physics. Medical radiology. Nuclear medicine 
690 |a R895-920 
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786 0 |n Journal of Indian Academy of Oral Medicine and Radiology, Vol 32, Iss 1, Pp 50-54 (2020) 
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