Disentangling the Complexity of a Hexa-Herbal Chinese Medicine Used for Inflammatory Skin Conditions-Predicting the Active Components by Combining LC-MS-Based Metabolite Profiles and in vitro Pharmacology

• Main Authors: Jennifer B. Chang (Author), Majella E. Lane (Author), Min Yang (Author), Michael Heinrich (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Fag: article
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Objectives: The purpose of this study is to investigate the anti-inflammatory activity of a hexa-herbal Chinese formula (HHCF) using spontaneously immortalized human epidermal keratinocytes (HaCaT) and to predict the active components by correlating the LC-MS-based metabolite profiles of the HHCF an...