Gadolinium-based coronary angiography in a patient with prior known anaphylaxis to iodine-based dye

Gadodiamide is a gadolinium-based chemical element that is considered safe and well tolerated in patients without renal dysfunction and is therefore routinely used as a contrast agent in magnetic resonance imaging. Although radio-opaque, it is not frequently used for coronary angiography due to its...

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Main Authors: Nirmal Guragai (Author), Sherif Roman (Author), Rahul Vasudev (Author), Upamanyu Rampal (Author), Preet Randhawa (Author), Fayez Shamoon (Author), Hartaj Virk (Author), Mahesh Bikkina (Author), JW Moses (Author), Apurva Motivala (Author)
Format: Book
Published: Greater Baltimore Medical Center, 2021-03-01T00:00:00Z.
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Summary:Gadodiamide is a gadolinium-based chemical element that is considered safe and well tolerated in patients without renal dysfunction and is therefore routinely used as a contrast agent in magnetic resonance imaging. Although radio-opaque, it is not frequently used for coronary angiography due to its less than optimal image quality and prohibitive cost. Our center's previous experience was less than satisfactory but the addition of a power injection system yielded good quality diagnostic images. We report a case of 63 years old male with a known history of severe, life-threatening anaphylactic reaction to previous iodinated dye presenting with persistent angina despite optimal medical therapy. Coronary and bypass graft angiography was performed using 24 cc of undiluted Gadodiamide (OMNISCAN) with a power injector (ACIST®) without any incidents or premedication with an interpretable angiogram.
Item Description:2000-9666
10.1080/20009666.2021.1890337