Methylglyoxal Accumulation in Arterial Walls Causes Vascular Contractile Dysfunction in Spontaneously Hypertensive Rats
Methylglyoxal (MGO) is a metabolite of glucose and perhaps mediates diabetes-related macrovascular complications including hypertension. In the present study, we examined if MGO accumulation affects vascular reactivity of isolated mesenteric artery from spontaneously hypertensive rats (SHR). Five-we...
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Main Authors: | Masashi Mukohda (Author), Muneyoshi Okada (Author), Yukio Hara (Author), Hideyuki Yamawaki (Author) |
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Format: | Book |
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Elsevier,
2012-01-01T00:00:00Z.
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