Combination of Dissolving Microneedles with Nanosuspension and Co-Grinding for Transdermal Delivery of Ketoprofen

• Main Authors: Delly Ramadon (Author), Fathin Ulayya (Author), Annisa Sakinah Qur'ani (Author), Iskandarsyah Iskandarsyah (Author), Yahdiana Harahap (Author), Qonita Kurnia Anjani (Author), Vania Aileen (Author), Pietradewi Hartrianti (Author), Ryan F. Donnelly (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ketoprofen is an anti-inflammatory agent that may cause gastric irritation if administered orally. Dissolving microneedles (DMN) can be a promising strategy to overcome this issue. However, ketoprofen has a low solubility; therefore, it is essential to enhance its solubility using certain methods, n...