Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer

• Main Authors: Zengya Guo (Author), Xiaofeng Wang (Author), Yuhan Yang (Author), Weiwei Chen (Author), Kundong Zhang (Author), Buwei Teng (Author), Chen Huang (Author), Qian Zhao (Author), Zhengjun Qiu (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The hypoxic microenvironment, an important feature of solid tumors, promotes tumor cells to release exosomes and enhances tumor angiogenesis. However, the detailed functions of hypoxic exosomes and the mechanisms underlying their effects in pancreatic cancer (PC) remain mysterious. Here, we observed...