Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury

• Main Authors: Ryan M. Williams (Author), Janki Shah (Author), Elizabeth Mercer (Author), Helen S. Tian (Author), Vanessa Thompson (Author), Justin M. Cheung (Author), Madeline Dorso (Author), Jaclyn M. Kubala (Author), Lorraine J. Gudas (Author), Elisa de Stanchina (Author), Edgar A. Jaimes (Author), Daniel A. Heller (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin-induced acute kidney injury (CI-AKI) is a significant co-morbidity of chemotherapeutic regimens. While this condition is associated with substantially lower survival and increased economic burden, there is no pharmacological agent to effectively treat CI-AKI. The disease is hallmarked by a...