Enzyme-mediated hydrolytic activation of prodrugs
Prodrug design is an important part of drug discovery. Prodrugs can offer many advantages over parent drugs such as increased solubility, enhanced stability, improved bioavailability, reduced side effects, and better selectivity. Many prodrugs have been used successfully in the clinic; examples incl...
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| Main Authors: | , , , , |
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| Format: | Book |
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Elsevier,
2011-10-01T00:00:00Z.
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