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Ovarian cancer mouse models: a summary of current models and their limitations

<p>Abstract</p> <p>Development of mouse models representing human spontaneous ovarian cancer has been hampered by the lack of understanding of the etiology of this very complex disease. Mouse models representing the different types of ovarian cancer are needed to understand how epi...

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Bibliographic Details
Main Authors: Fong Miranda Y (Author), Kakar Sham S (Author)
Format: Book
Published: BMC, 2009-09-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Fong Miranda Y  |e author 
700 1 0 |a Kakar Sham S  |e author 
245 0 0 |a Ovarian cancer mouse models: a summary of current models and their limitations 
260 |b BMC,   |c 2009-09-01T00:00:00Z. 
500 |a 10.1186/1757-2215-2-12 
500 |a 1757-2215 
520 |a <p>Abstract</p> <p>Development of mouse models representing human spontaneous ovarian cancer has been hampered by the lack of understanding of the etiology of this very complex disease. Mouse models representing the different types of ovarian cancer are needed to understand how epithelial ovarian cancer differs from granulosa cell tumors. Many different methods have been used to generate a viable genetic model with limited success. This review focuses on the methods of various investigators and the limitations of each model in establishing a reproducible and inheritable line to study this disease.</p> 
546 |a EN 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Journal of Ovarian Research, Vol 2, Iss 1, p 12 (2009) 
787 0 |n http://www.ovarianresearch.com/content/2/1/12 
787 0 |n https://doaj.org/toc/1757-2215 
856 4 1 |u https://doaj.org/article/ea15a68b6a904277a62b8d33f55ff64c  |z Connect to this object online. 

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