A suspected case of "itai-itai disease" in a cadmium-polluted area in Akita prefecture, Japan
Background: Itai-itai disease is the most severe case of chronic cadmium (Cd) toxicity, which was endemic in Cd-polluted areas in the Jinzu River basin in Toyama prefecture, Japan. Akita prefecture also has Cd-polluted areas, but there have been no cases of "itai-itai disease". Case presen...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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Komiyama Printing Co. Ltd,
2024-08-01T00:00:00Z.
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| Summary: | Background: Itai-itai disease is the most severe case of chronic cadmium (Cd) toxicity, which was endemic in Cd-polluted areas in the Jinzu River basin in Toyama prefecture, Japan. Akita prefecture also has Cd-polluted areas, but there have been no cases of "itai-itai disease". Case presentation: An elderly female farmer with Cd nephropathy residing in a Cd-polluted area in the northern part of the Akita prefecture was identified through hospital-based screening at Akita Rosai Hospital in Odate city. She had chronic renal failure with a high Cd exposure level and advanced renal tubular dysfunction. The shortening of height, bone deformities and fractures, abnormal bone metabolism suggesting osteomalacia, and renal anemia were also noted. Therefore, "itai-itai disease", similar to cases in the Jinzu River basin, was suspected. Conclusion: This is the first case of "itai-itai disease" in a Cd-polluted area in Akita prefecture. |
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| Item Description: | 1342-078X 1347-4715 10.1265/ehpm.24-00063 |