CRISPR/Cas9 Ablated BCL11A Unveils the Genes with Possible Role of Globin Switching

• Những tác giả chính: Fatemeh Movahedi Motlagh (Tác giả), Hamid Reza Soleimanpour‐Lichaei (Tác giả), Mehdi Shamsara (Tác giả), Azadeh Etemadzadeh (Tác giả), Mohammad Hossein Modarressi (Tác giả)
• Định dạng: Sách
• Được phát hành: Tabriz University of Medical Sciences, 2023-11-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Purpose: Fetal hemoglobin (HbF) upregulation is a mitigating factor in β-hemoglobinopathies therapy like β-thalassemia and sickle cell diseases. Finding molecular mechanisms and the key regulators responsible for globin switching could be helpful to develop effective ways to HbF upregulation. In our...