Analysis of drug interactions and epidemiological profile of individuals with diabetes mellitus in primary care

• Main Authors: Leila Zanatta (Author), Fernanda Norbak Dalla Cort (Author), Nathalya Silva Mathias (Author), Carla Argenta (Author)
• Format: Book
• Published: Universidade Federal de Santa Maria, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2179-7692; 2179-7692; 10.5902/2179769240175
• Keywords: diabetes mellitus; hipoglicemiantes; enfermagem; polimedicação; Medicine; R; Nursing; RT1-120
• Source: Revista de Enfermagem da Universidade Federal de Santa Maria, Vol 10, Iss 0, Pp e47-e47 (2020)

Aim: to analyze drug interactions and the epidemiological profile of individuals with diabetes mellitus (DM). Method: quantitative study with the application of a questionnaire to 42 patients with DM belonging to a Family Health Center (FHC). Data were collected in 2018, in three stages: meeting at the CSF, home visits and searching electronic medical records; followed by analysis of drug interactions in the Drug Interactions Checker Drug Information and DrugBank databases. Results: the mean age of the patients was 68.36 years. The total number of associations between drugs was 1355 (mean 32.26 / patient). The total number of medications that interact was 479 (11.40 interactions /patient). In 65% the combinations did not interact, 4% were mild interactions, 26.05% moderate and 1.70% severe. Conclusion: the number of drug interactions is significant, with a moderate degree predominating. The age of patients and the presence of comorbidities can be associated with polymedication, contributing to the occurrence of these interactions.