Sporoderm-Broken Spores of Ganoderma lucidum Sensitizes Ovarian Cancer to Cisplatin by ROS/ERK Signaling and Attenuates Chemotherapy-Related Toxicity

• Main Authors: Kaili Cen (Author), Ming Chen (Author), Mengye He (Author), Zhenhao Li (Author), Yinjing Song (Author), Pu Liu (Author), Qi Jiang (Author), Suzhen Xu (Author), Yunlu Jia (Author), Peng Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although platinum-based chemotherapeutics such as cisplatin are the cornerstone of treatment for ovarian cancer, their clinical application is profoundly limited due to chemoresistance and severe adverse effects. Sporoderm-broken spores of Ganoderma lucidum (SBSGL) have been reported to possess anti...