Encapsulation of Asparaginase as a Promising Strategy to Improve In Vivo Drug Performance

• Autori principali: Francisca Villanueva-Flores (Autore), Andrés Zárate-Romero (Autore), Alfredo G. Torres (Autore), Alejandro Huerta-Saquero (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2021-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Asparaginase (ASNase) is a widely applied chemotherapeutic drug that is used to treat Acute Lymphoblastic Leukemia (ALL); however, immune responses and silent inactivation of the drug often limit its bioavailability. Many strategies have been proposed to overcome these drawbacks, including the devel...