The Role of High-Mobility Group Box-1 and Its Crosstalk with Microbiome in Rheumatoid Arthritis

• Hlavní autoři: Federico Biscetti (Autor), Andrea Flex (Autor), Stefano Alivernini (Autor), Barbara Tolusso (Autor), Elisa Gremese (Autor), Gianfranco Ferraccioli (Autor)
• Médium: Kniha
• Vydáno: Hindawi Limited, 2017-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic, definitely disabling, and potentially severe autoimmune disease. Although an increasing number of patients are affected, a key treatment for all patients has not been discovered. High-mobility group box-1 (HMGB1) is a nuclear protein passively and actively rel...