Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma
RNA interference (RNAi) allows the specific knockdown of tumor relevant genes. To induce RNAi, the delivery of small interfering RNAs (siRNAs) is of crucial importance. This is particularly challenging for their therapeutic applications in vivo. Low molecular weight branched polyethylenimine (PEI) i...
Saved in:
Main Authors: | Achim Aigner (Author), Chantal C.M. Appeldoorn (Author), Sabrina Höbel (Author), Pieter J. Gaillard (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2011-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Antiproliferative activity of CD44 siRNA-PEI-PEG nanoparticles in glioblastoma: involvement of AKT signaling
by: Parvaneh Mahinfar, et al.
Published: (2022) -
Liver-Targeted Combination Therapy Basing on Glycyrrhizic Acid-Modified DSPE-PEG-PEI Nanoparticles for Co-delivery of Doxorubicin and Bcl-2 siRNA
by: Guixiang Tian, et al.
Published: (2019) -
Using RNAi in the treatment of cardiovascular diseases - therapeutics based on siRNA overview
by: Barbara Rusinowska
Published: (2022) -
Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson's Disease
by: Christin Helmschrodt, et al.
Published: (2017) -
Voltage Preconditioning Allows Modulated Gene Expression in Neurons Using PEI-complexed siRNA
by: Arati Sridharan, et al.
Published: (2013)