Nightshift work job exposure matrices and urinary 6-sulfatoxymelatonin levels among healthy Chinese women
OBJECTIVE: Six-sulfatoxymelatonin (aMT6s) is a primary urinary metabolite of melatonin. We examined the association between aMT6s levels and shift work estimated by a job exposure matrix (JEM) among healthy participants of the Shanghai Women's Health Study. METHODS: Creatinine-adjusted aMT6s le...
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| Format: | Book |
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Nordic Association of Occupational Safety and Health (NOROSH),
2012-11-01T00:00:00Z.
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|---|---|---|---|
| 001 | doaj_eb25baba6c9f4fc4891b93c66f7769c5 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Bu-Tian Ji |e author |
| 700 | 1 | 0 | |a Yu-Tang Gao |e author |
| 700 | 1 | 0 | |a Xiao-Ou Shu |e author |
| 700 | 1 | 0 | |a Gong Yang |e author |
| 700 | 1 | 0 | |a Kai Yu |e author |
| 700 | 1 | 0 | |a Shou-Zheng Xue |e author |
| 700 | 1 | 0 | |a Hong-Lan Li |e author |
| 700 | 1 | 0 | |a Linda M Liao |e author |
| 700 | 1 | 0 | |a Aaron Blair |e author |
| 700 | 1 | 0 | |a Nathaniel Rothman |e author |
| 700 | 1 | 0 | |a Wei Zheng |e author |
| 700 | 1 | 0 | |a Wong-Ho Chow |e author |
| 245 | 0 | 0 | |a Nightshift work job exposure matrices and urinary 6-sulfatoxymelatonin levels among healthy Chinese women |
| 260 | |b Nordic Association of Occupational Safety and Health (NOROSH), |c 2012-11-01T00:00:00Z. | ||
| 500 | |a 0355-3140 | ||
| 500 | |a 1795-990X | ||
| 500 | |a 10.5271/sjweh.3322 | ||
| 520 | |a OBJECTIVE: Six-sulfatoxymelatonin (aMT6s) is a primary urinary metabolite of melatonin. We examined the association between aMT6s levels and shift work estimated by a job exposure matrix (JEM) among healthy participants of the Shanghai Women's Health Study. METHODS: Creatinine-adjusted aMT6s levels were measured in the urine samples of 300 women and related to JEM shift work categories. RESULTS: Adjusted geometric means of aMT6s levels from urine samples collected before 08:00 hours were lower among persons holding nighttime shift work jobs. The adjusted aMT6s levels (ng/mg creatinine) were 8.36 [95% confidence intervals (95% CI) 4.47-15.6], 6.37 (95% CI 3.53-11.5), 6.20 (95% CI 3.33-11.5), 3.81 (95% CI 2.02-7.19), and 3.70 (95% CI 1.92-7.11) from the lowest (never held a shift work job) to the highest (current job likely involved all-night shift work) shift work JEM scores (P=0.05). CONCLUSION: Our results indicate that nightshift work JEM scores were significantly and inversely associated with aMT6s levels in early morning spot urine samples collected between 07:00-08:00 hours. | ||
| 546 | |a EN | ||
| 690 | |a cancer | ||
| 690 | |a china | ||
| 690 | |a shift work | ||
| 690 | |a melatonin | ||
| 690 | |a woman | ||
| 690 | |a night shift | ||
| 690 | |a job exposure matrix | ||
| 690 | |a nighttime work | ||
| 690 | |a urinary 6-sulfatoxymelatonin | ||
| 690 | |a amt6s | ||
| 690 | |a urine sample | ||
| 690 | |a Public aspects of medicine | ||
| 690 | |a RA1-1270 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Scandinavian Journal of Work, Environment & Health, Vol 38, Iss 6, Pp 553-559 (2012) | |
| 787 | 0 | |n https://www.sjweh.fi/show_abstract.php?abstract_id=3322 | |
| 787 | 0 | |n https://doaj.org/toc/0355-3140 | |
| 787 | 0 | |n https://doaj.org/toc/1795-990X | |
| 856 | 4 | 1 | |u https://doaj.org/article/eb25baba6c9f4fc4891b93c66f7769c5 |z Connect to this object online. |