An Overview of the Biological Activity of Pyrrolo[3,4-<i>c</i>]pyridine Derivatives

Pyrrolo[3,4-<i>c</i>]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-<i>c</i>]pyridine derivatives is the main reason for develop...

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Bibliographic Details
Main Authors: Anna Wójcicka (Author), Aleksandra Redzicka (Author)
Format: Book
Published: MDPI AG, 2021-04-01T00:00:00Z.
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Summary:Pyrrolo[3,4-<i>c</i>]pyridine is one of the six structural isomers of the bicyclic ring system containing a pyrrole moiety fused to a pyridine nucleus. The broad spectrum of pharmacological properties of pyrrolo[3,4-<i>c</i>]pyridine derivatives is the main reason for developing new compounds containing this scaffold. This review presents studies on the biological activity of pyrrolo[3,4-<i>c</i>]pyridines that have been reported in the scientific literature. Most of these derivatives have been studied as analgesic and sedative agents. Biological investigations have shown that pyrrolo[3,4-<i>c</i>]pyridines can be used to treat diseases of the nervous and immune systems. Their antidiabetic, antimycobacterial, antiviral, and antitumor activities also have been found.
Item Description:10.3390/ph14040354
1424-8247