COMORBIDITY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A ROLE OF CARDIOVASCULAR DISORDERS

• Main Authors: N. A. Karoli (Author), A. P. Rebrov (Author)
• Format: Book
• Published: Столичная издательская компания, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<p><strong>Aim.</strong> To study prevalence and features of cardiovascular diseases (arterial hypertension, ischemic heart disease, chronic heart failure) in patients with chronic obstructive pulmonary disease (COPD).</p><p><strong>Material and methods.</strong> 233 patients with COPD (229 men, 4 women; 55,3±0,6 y.o.) were examined. General clinical examination, including body mass index calculation, 6-min walk test, blood analysis, electrocardiography, echocardiography, investigation of respiratory function, pulsoxymetry was carried out. Cardiac Infarction Injury Score (CIIS) index was also evaluated.</p><p><strong>Results.</strong> COPD is associated with arterial hypertension in 62,2% of cases, ischemic heart disease - 27%, carotid atherosclerosis - 43,6%, chronic heart failure in 23,6% of cases. Risk factors of ischemic heart disease in COPD patients include: age, COPD severity, bronchial obstruction severity (decrease of forced expiratory volume), systemic inflammation (high level of C-reactive protein). Patients with severe and very severe COPD had CIIS index >20 1,8 times more often than patients with moderate COPD. Significant correlation of CIIS index with pulmonary hypertension (r=0,21, p<0,05), end-diastolic dimension of right ventricle (r=0,24, p<0,05) and left ventricle (r=0,33, p<0,05), left ventricle ejection fraction (r=-0,40, p<0,01) was found.</p><p><strong>Conclusion.</strong> COPD is associated with cardiovascular diseases. CIIS index can help to detect previous myocardial infarction in COPD patients.</p>

Item Description

1819-6446
2225-3653
10.1234/1819-6446-2009-4-9-16