Roles and molecular mechanisms of physical exercise in cancer prevention and treatment

Exercise can enhance motivation to change lifestyle behaviors, improve aerobic fitness, improve physical function, control fatigue, and enhance quality of life. Studies have demonstrated the benefits to be gained from physical exercise, highlighting the importance of popularizing the concept of phys...

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Bibliographic Details
Main Authors: Qiaoyun Wang (Author), Wenli Zhou (Author)
Format: Book
Published: Elsevier, 2021-03-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Qiaoyun Wang  |e author 
700 1 0 |a Wenli Zhou  |e author 
245 0 0 |a Roles and molecular mechanisms of physical exercise in cancer prevention and treatment 
260 |b Elsevier,   |c 2021-03-01T00:00:00Z. 
500 |a 2095-2546 
500 |a 10.1016/j.jshs.2020.07.008 
520 |a Exercise can enhance motivation to change lifestyle behaviors, improve aerobic fitness, improve physical function, control fatigue, and enhance quality of life. Studies have demonstrated the benefits to be gained from physical exercise, highlighting the importance of popularizing the concept of physical exercise for individuals and making professional exercise-treatment programs available to patients with cancer. However, the correlation between physical exercise and carcinogenesis is easily overlooked, and exercise interventions are not routinely provided to patients with cancer, especially those with advanced cancer. In this article, we present a literature review of the effects of exercise on cancer development and progression and give recent evidence for the type of exercise best suited for different types of cancer and in different disease stages. Moreover, the molecular mechanisms about regulating metabolism and systemic immune function in cancer are summarized and discussed. In conclusion, physical exercise should be considered as an important intervention for preventing and treating cancer and its complications. 
546 |a EN 
690 |a Cancer development 
690 |a Cancer treatment 
690 |a Molecular mechanisms 
690 |a Physical exercise 
690 |a Sports 
690 |a GV557-1198.995 
690 |a Sports medicine 
690 |a RC1200-1245 
655 7 |a article  |2 local 
786 0 |n Journal of Sport and Health Science, Vol 10, Iss 2, Pp 201-210 (2021) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2095254620300958 
787 0 |n https://doaj.org/toc/2095-2546 
856 4 1 |u https://doaj.org/article/eb4da212cc3c450581567b8cbc7c5f0a  |z Connect to this object online.