Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

• Κύριοι συγγραφείς: Mica Ohara-Imaizumi (Συγγραφέας), Kyota Aoyagi (Συγγραφέας), Toshihisa Ohtsuka (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Elsevier, 2019-09-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca2+-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; however...