Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

• Հիմնական հեղինակներ: Mica Ohara-Imaizumi (Հեղինակ), Kyota Aoyagi (Հեղինակ), Toshihisa Ohtsuka (Հեղինակ)
• Ձևաչափ: Գիրք
• Հրապարակվել է: Elsevier, 2019-09-01T00:00:00Z.
• Խորագրեր: article
• Առցանց հասանելիություն: Connect to this object online.

Background: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca2+-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; however...