Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

• 主要な著者: Mica Ohara-Imaizumi (著者), Kyota Aoyagi (著者), Toshihisa Ohtsuka (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2019-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca2+-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; however...