Role of the active zone protein, ELKS, in insulin secretion from pancreatic β-cells

• Главные авторы: Mica Ohara-Imaizumi (Автор), Kyota Aoyagi (Автор), Toshihisa Ohtsuka (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2019-09-01T00:00:00Z.
• Предметы: article
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Background: Insulin is stored within large dense-core granules in pancreatic beta (β)-cells and is released by Ca2+-triggered exocytosis with increasing blood glucose levels. Polarized and targeted secretion of insulin from β-cells in pancreatic islets into the vasculature has been proposed; however...