The Effect of Lamotrigine on Nav1.4 Voltage-Gated Sodium Channels
Lamotrigine (LTG) is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder and it has been known that LTG targets voltage-dependent sodium channels (VGSCs). In this study, we investigated the effect of LTG on the Nav1.4 Na+ current using HEK293 cells expressing mouse Nav1.4 V...
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Main Authors: | Yoshihiko Nakatani (Author), Haruka Masuko (Author), Taku Amano (Author) |
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Format: | Book |
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Elsevier,
2013-01-01T00:00:00Z.
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