Repositioning of HMG-CoA Reductase Inhibitors as Adjuvants in the Modulation of Efflux Pump-Mediated Bacterial and Tumor Resistance
Efflux pump (EP)-mediated multidrug resistance (MDR) seems ubiquitous in bacterial infections and neoplastic diseases. The diversity and lack of specificity of these efflux mechanisms raise a great obstacle in developing drugs that modulate efflux pumps. Since developing novel chemotherapeutic drugs...
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Main Authors: | Zsuzsanna Schelz (Author), Hiba F. Muddather (Author), István Zupkó (Author) |
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Format: | Book |
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MDPI AG,
2023-09-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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