yCD/HPyCD Mixtures as Solubilizer: Solid-State Characterization and Sample Dexamethasone Eye Drop Suspension

• Main Authors: Phatsawee Jansook (Author), Garnpimol C. Ritthidej (Author), Haruhisa Ueda (Author), Einar Stefánsson (Author), Thorsteinn Loftsson (Author)
• Format: Book
• Published: Frontiers Media S.A., 2010-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. Study the complexation of dexamethasone in combinations of y-cyclodextrin (yCD) and 2-hydroxypropyl-y-cyclodextrin (HPyCD) with emphasis on solid characterization and development of aqueous dexamethasone eye drop suspension for drug delivery through sclera. Methods. Dexamethasone/cyclodextr...