Famotidine promotes inflammation by triggering cell pyroptosis in gastric cancer cells

• Main Authors: Jin Huang (Author), Pingsheng Fan (Author), Miao Liu (Author), Chengtao Weng (Author), Gaofei Fan (Author), Tengyue Zhang (Author), Xiaohong Duan (Author), Yang Wu (Author), Lili Tang (Author), Guohong Yang (Author), Yabei Liu (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cell pyroptosis has been characterized by cell swelling and pro-inflammatory factors release to aggravate inflammatory reaction., such as interlukin-1 beta (IL-1β) and interlukin18 (IL-18). However, the function of famotidine, an antagonist of histamine H2-receptor antagonists, i...