Poliovirus shedding after the first and second doses of trivalent polio vaccines in newborns

• Main Authors: Viramitha K. Rusmil (Author), Meita Dhamayanti (Author), Sunarjati Soedigdo Adi (Author), Imam Megantara (Author)
• Format: Book
• Published: Indonesian Pediatric Society Publishing House, 2015-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background The trivalent oral polio vaccine (tOPV) produced by Bio Farma consists of three live, attenuated poliovirus serotypes (1, 2, and 3). The tOPV stimulates the formation of secretory IgA (sIgA) on the intestinal wall and lumen. The existence of sIgA is considered giving immunity in the intes...