An Italian multicentre distributed data research network to study the use, effectiveness, and safety of immunosuppressive drugs in transplant patients: Framework and perspectives of the CESIT project

• Main Authors: Valeria Belleudi (Author), Alessandro C. Rosa (Author), Marco Finocchietti (Author), Francesca R. Poggi (Author), Maria Lucia Marino (Author), Marco Massari (Author), Stefania Spila Alegiani (Author), Lucia Masiero (Author), Andrea Ricci (Author), Gaia Bedeschi (Author), Francesca Puoti (Author), Massimo Cardillo (Author), Silvia Pierobon (Author), Maurizio Nordio (Author), Eliana Ferroni (Author), Martina Zanforlini (Author), Giuseppe Piccolo (Author), Olivia Leone (Author), Stefano Ledda (Author), Paolo Carta (Author), Donatella Garau (Author), Ersilia Lucenteforte (Author), Marina Davoli (Author), Antonio Addis (Author), CESIT Study Group (Author), Nera Agabiti (Author), Michele Ercolanoni (Author), Pamela Fiaschetti (Author), Bedeschi Gaia (Author), Valentina Ientile (Author), Ursula Kirchmayer (Author), Luca L'Abbate (Author), Lorella Leoni (Author), Olivia Lombardozzi (Author), Claudia Lucia Marino (Author), Maria Marino (Author), Arianna Mazzone (Author), Ugo Moretti (Author), Andrea Angelo Nisic (Author), Alessandra Oliveti (Author), Daniela Peritore (Author), Andrea Rosa (Author), Alessandro C. Ricci (Author), Vito Sparacino (Author), Matilde Tanaglia (Author), Silvia Trapani (Author), Gianluca Trifirò (Author), Manuel Zorzi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The goal of post-transplant immunosuppressive drug therapy is to prevent organ rejection while minimizing drug toxicities. In clinical practice, a multidrug approach is commonly used and involves drugs with different mechanisms of action, including calcineurin inhibitors (CNI) (tacrolimus or cyclosp...